Micro-Computed Tomography for the Evaluation of Bone Architecture
نویسنده
چکیده
Micro-computed tomography (micro-CT) is an emerging technique for the nondestructive assessment and analysis of the three-dimensional trabecular bone structure. Trabecular bone consists of a complicated three-dimensional network of plates and rods, arranged in a lattice-like network [1]. Aging, disease process, and therapeutic agents could influence the number of elements in this network, their dimensions and connectivity, thereby causing dramatic changes in bone strength [3]. Until recently information about these structural parameters of trabecular bone were only available by histomorphometry, a destructive procedure limited to two-dimensional analysis. On the other side, micro-CT is nondestructive and truly three-dimensional by nature, and therefore has found large applications in basic as well as pre-clinical bone research throughout the last several years.
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